PROGNOSTIC BIOMARKERS IN THE MANAGEMENT OF SICKLE CELL DISORDER PATIENTS OF ODISHA.

Abstract

The predictive and diagnostic information about the patient’s health condition is provided by routinely monitoring the haematological and biochemical parameters. The current study focused at how hematobiochemical parameters affected the pathophysiology of sickle cell disease (SCD) patients. Finally, the hematobiochemical profiles of 167 SCD (HbSS) patients are investigated. SCD patients had reduced haemoglobin levels. They have elevated retics, HbF, and LDH. Billirubin, Hb, and LDH were found to be indicators of disease severity in this research. As a result, bilirubin, haemoglobin, and LDH can be used as biomarkers in sickle cell disease patients. Early diagnosis of LDH and monitering of these factors can result in improved patient outcomes in sickle cell disease patients.